OncoGel (ReGel/paclitaxel) — Clinical applications for a novel paclitaxel delivery system
✍ Scribed by Nancy L. Elstad; Kirk D. Fowers
- Book ID
- 113418351
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 231 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0169-409X
No coin nor oath required. For personal study only.
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## Abstract A hyperbranched aliphatic polyester has been functionalized with PEG chains to afford a novel water‐soluble BH40‐PEG polymer which exhibits unimolecular micellar properties, and is therefore appropriate for application as a drug‐delivery system. The solubility of the anticancer drug pac
Paclitaxel is a potent chemotherapeutic agent currently administered intravenously in polyoxyethylated castor oil (Cremophor EL) and dehydrated ethanol (1:1) for the treatment of solid tumors. The objective of this work was to develop a novel self-emulsifying drug delivery system (SEDDS) devoid of c