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On the synthesis of 3-amino-2,3-dihydro-1H-pyrido[3,2,1-kl]phenothiazine 5,5-dioxide and of 3-amino-1,2-dihydro-3H-dibenzo[c,jk]pyrido[2,1-c]-1,4-thiazepine 7,7-Dioxide

✍ Scribed by P. Catsoulacos; M. Pelecanou; Ch. Camoutsis


Book ID
112130109
Publisher
Journal of Heterocyclic Chemistry
Year
1991
Tongue
English
Weight
277 KB
Volume
28
Category
Article
ISSN
0022-152X

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Synthesis of 1-methyl-7-(trifluoromethyl
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## Abstract The reaction of methyl 2‐bromo‐6‐(trifluoromethyl)‐3‐pyridinecarboxylate (1) with methanesulfonamide gave methyl 2‐[(methylsulfonyl)amino]‐6‐(trifluoromethyl)‐3‐pyridine‐carboxylate (2). Alkylation of compound 2 with methyl iodide followed by cyclization of the resulting methyl 2‐[methy