On the surface inactivation of pepsin
β Scribed by D.F Cheesman; H Schuller
- Publisher
- Elsevier Science
- Year
- 1954
- Weight
- 506 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0095-8522
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π SIMILAR VOLUMES
Alkylperoxy radicals containing one, two or three chlorine atoms, 'CO;, 0, '\_ and HO, ' were reacted with pepsin in aqueous solutions. It was found that only Cl,COO' and 'CO; inactivate pepsin, attacking preferentially the disulfide bridge. Transient spectra obtained upon completion of the Cl,COO'
Dilutions of human sera containing between 10(3) and 10(5) chimpanzee infectious doses of hepatitis B virus per ml, subtype adr or ayw, were treated with either 1 microgram/ml pepsin at pH 2.0 for 18 hours, 8 M urea for four hours, or 1:4,000 formalin for 72 hours. One ml of the serum containing hep
Pepsin is of interest for many reasons, but attention is directed here to it as representing those enzymes that probably contain no prosthetic (nonamino acid) groups. Its proteolytic activity must, therefore, be attributed to the arrangement of its amino acids in the peptide chain and/or to the fold