TEE alkaloid 8tvpidoepermine obtained from the bark of Aspidosperma auebraaho blanoo and first studied by Ewina' in 1914 has been the subjeot of aotlve chemioal study shoe 1947. It has proved to be a member of that increasingly large bixly of natural product8 whose molecular structure eludes un8mbig
On the structure of aspidospermine
β Scribed by Harold Conroy; Peter R. Brook; Yaacov Amiel
- Publisher
- Elsevier Science
- Year
- 1959
- Tongue
- French
- Weight
- 370 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
IN Part II2 vs outlined the development of the partial structural formula (I) for the alkaloid arpidoqmmine. The additional ohemiaaf widenoe domcribed iu thim Letter oohfirms thome oonolusious and has a oonsiderabla further beariug on the struoture. While mainly limited to elucidation of the nature of rings D aud E enolosiug the basio nitrogen (hb), our results 1 2 Part III of a series. Contribution numbered 1570 from the Sterling Chemistry Laboratory at Yale University. 8. COXWOY, P. a. Brook, Y. IT. Bout and N. Silverman, J. Amer. asq &SO, 5178 (1958).
π SIMILAR VOLUMES
In the preceding papers (l), we reported that a-7-keto-decahydroquinoline was synthesized by the method of Grob (2) and derived to I in a similar way for synthesis of dl-aspldospermine(V) (3,4). The structure of the compound(I) was proved to be Ia, whose n.m.r. spectrum was well similar to that of o