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On the structure of acyl nitroxides (nitroxones). Spin trapping aminoacyl radicals with t-nitrosobutane (t-NB) and phenyl t-butyl nitrone (PBN)

✍ Scribed by Edward G. Janzen; Edward R. Davis; Dale E. Nutter Jr.


Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
240 KB
Volume
19
Category
Article
ISSN
0040-4039

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✦ Synopsis


a-Ketonitroxides (nitroxones) are relatively persistent nitroxides produced either from oxidation of hydroxamic acids (1) or by spin trapping (2). Since nitroxones are isoelectronic with semidiones (3) it is reasonable to assume that the carbonyl and nitroxyl functions are part of a planar 5n-electron system (4,5). This assumption implies that the unpaired electron is delocalized over all four atoms of the x-system (4). Thus finite spin density