On the Role of the Crystal Environment in Determining Protein Side-chain Conformations
β Scribed by Matthew P. Jacobson; Richard A. Friesner; Zhexin Xiang; Barry Honig
- Book ID
- 117142856
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 1000 KB
- Volume
- 320
- Category
- Article
- ISSN
- 0022-2836
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π SIMILAR VOLUMES
A model of nine proteins including side-chain atoms have been built from the known C a coordinates and amino acid sequences using a Monte Carlo Protein Building Annealing method. The Cartesian coordinates for the side-chain atoms were established with bond lengths and angles selected randomly from w
## Abstract We introduce a family of procedures designed to sample sideβchain conformational space at particular locations in protein structures. These procedures (CRSP) use intensive cycles of random assignment of sideβchain conformations followed by minimization to determine all the conformations