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On the role of phosphorylated intermediates in sodium and potassium stimulated ATP-hydrolysis

✍ Scribed by W. Schoner; R. Kramer; W. Seubert


Book ID
118849925
Publisher
Elsevier Science
Year
1966
Tongue
English
Weight
299 KB
Volume
23
Category
Article
ISSN
0006-291X

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Pump-leak parallelism in sodium-absorbin
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In all Na(+)-absorbing and Cl(-)-secreting epithelia, an increase in the activity of the Na+,K(+)-pump at the basolateral membrane is accompanied by an increase in the K+ conductance of that barrier and vice versa. We have recently identified an ATP-regulated K+ channel, K(ATP), in basolateral membr