On the role of astrocytes in polyclonal T cell activation
β Scribed by B. Schnyder; E. Weber; W. Fierz; A. Fontana
- Book ID
- 119106748
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 418 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0165-5728
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## Abstract Resident T lymphocytes have been found to exert helper and suppressor regulatory influences with regard to polyclonal activation of murine splenic B lymphocytes elicited by lipopolysaccharide. In the normal adult spleen, only T cell helper influences are exercised over polyclonal B cell
It has previously been reported (Hiinig, T. et al., Eur. J. Zmmunol. 1983. 13: 1) that highly purified peripheral T cells do not respond to concanavalin A (Con A) even in the presence of Con A-induced spleen cell supernatant as a source of interleukin 2 (IL 2). In the present report, the hypothesis