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On the role of 26-deoxylaidlomycin in laidlomycin biosynthesis

✍ Scribed by Dr. U. Gräfe; C. Stengel

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
240 KB
Volume
31
Category
Article
ISSN
0233-111X

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✦ Synopsis

3H-26-deoxylaidlomycin (I) was fed to growing cultures of Streptoverticillium olivoreticuli IMET 43782 producing both I and laidlomycin (II). The incorporation of labelled I into laidlomycin II was neglible showing a role of I as precursor of II to be at variance. Otherwise, a measurable conversion was achieved by the use of sonicated 48 hrs mycelium suggesting that final oxidation of I to II could be mediated by a compartmentized oxidoreductase.

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