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On the relations between virus-induced mutation and neoplastic transformation in rodent and human cells

✍ Scribed by M. Theile; H. Waehlte; L. Luebbe; H. Krause; S. Scherneck; M. Strauss; E. Geissler

Book ID
113250422
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
121 KB
Volume
97
Category
Article
ISSN
0165-1161

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We introduced the mutant p53 zene (codon 273Ar9-His) into human fibroblasts (SUSM-I ceils) previously immortalized with 4-nitroquinoline I -oxide (4NQO) and obtained 2 clonal cell lines (SUSM-I /p53-I and SUSM-l/p53-6) expressing the mutant p53. Since the genetic background of SUSM-l/p53 is the same