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On the problem of immunological detection of antigens in skeletal remains

✍ Scribed by Eugenio Lendaro; Rodolfo Ippoliti; Andrea Bellelli; Maurizio Brunori; Romano Zito; Gennaro Citro; Antonio Ascenzi

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 345 KB
Volume: 86
Category: Article
ISSN: 0002-9483
DOI: 10.1002/ajpa.1330860308

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A detailed investigation with affinity‐chromatography‐purified fractions of antihemoglobin serum from rabbit shows that the hemoglobin content of human bones dating back 15 to 3,000 years may be very small. Some of the previous results (Ascenzi et al., 1985) indicating a high hemoglobin titer were vitiated because of an unexpected cross‐reactivity of bone extracts with the hemoglobin‐unreactive fraction of the antiserum.

This study calls attention to possible artifacts intrinsic to the application of immunological techniques to the study of archaeological samples.

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