✦ LIBER ✦

On the presence of met 5-enkephalin receptors on the plasma membrane of deiters'neurons and their modulation of GABA transport

✍ Scribed by Aroldo Cupello; Holger Hydén

Book ID: 102382857
Publisher: John Wiley and Sons
Year: 1981
Tongue: English
Weight: 314 KB
Volume: 6
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.490060504

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✦ Synopsis

Abstract

Met 5‐enkephalin blocks the active transport of GABA across plasma membranes of rabbit Deiters' neurons prepared by microdissection. Such an effect is receptor‐mediated, being reversed by the antagonist Naloxone.

This result shows that Deiters' neurons bear enkephalin receptors, and suggests a hypothesis on the mechanism of enkephalin‐mediated neuronal inhibition.

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