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On the Physical Basis of the Amino Acid Polar Requirement

✍ Scribed by Damien C. Mathew; Zaida Luthey-Schulten

Publisher
Springer
Year
2008
Tongue
English
Weight
566 KB
Volume
66
Category
Article
ISSN
0022-2844

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πŸ“œ SIMILAR VOLUMES

Amino acid architecture and the distribu
Amino acid architecture and the distribution of polar atoms on the surfaces of proteins
✍ H. P. Shanahan; J. M. Thornton πŸ“‚ Article πŸ“… 2005 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 614 KB

## Abstract We propose that a necessary condition for a protein to be soluble is the absence of large hydrophobic patches on its solvent‐accessible surface, which can cause aggregation to occur. We note that the polar nature of the backbone of all amino acids guarantees a minimum polar content and