The pharmacokinetics and metabolism of m
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Gerhard Ehninger; Barbara Proksch; Gerhard Heinzel; Erdmute Schiller; Karl-Heinz
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Article
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1985
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Springer US
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English
⚖ 470 KB
An HPLC method using paired-ion chromatography on RP C-18 material was developed. After sample clean up on XAD columns, mitoxantrone (Novantrone; dihydroxyanthracenedione) in concentrations below 1 ng/ml in serum and 0.2 ng/ml in urine were measurable with a coefficient of variation less than 9.3% a