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On the odor of the enantiomers of Madrol®

✍ Scribed by Gerhard Buchbauer; Philippine Lebada; Lucia Wiesinger; Petra Weiss-Greiler; Peter Wolschann

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
235 KB
Volume
9
Category
Article
ISSN
0899-0042

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✦ Synopsis

The asymmetric syntheses of the enantiomers of Madrol (1) are described and their odor properties evaluated. ( )-(-)-1 exerts a powerful sandalwood odor with some animalic undertones, whereas its antipode smells sweet and flowery rather than like sandalwood. Molecular surface comparisons show remarkable deviations in the hydrophobic parts of the two enantiomers. Chirality 9: 380-385, 1997.

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