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On the molecular basis of pyruvate kinase deficiency II. Role of thiol groups in pyruvate kinase from pyruvate kinase-deficient patients

✍ Scribed by Th.J.C. Van Berkel; G.E.J. Staal; J.F. Koster; J.G. Nyessen; L. van Milligen-Boersma


Book ID
115733622
Publisher
Elsevier Science
Year
1974
Weight
396 KB
Volume
334
Category
Article
ISSN
0005-2744

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## Abstract In this study, possible adverse effects of pyruvate kinase (PK) deficiency on the maturation of erythroid progenitors were investigated. A 4‐year‐old Japanese girl with severe PK deficiency underwent splenectomy to reduce her need for blood transfusions. The spleen was examined a histol