On the mechanism of action of GTP-transf
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Mark J. Dufton; Colin L. Gibson; Andrew R. Pitt; Salah Athmani; Colin J. Sucklin
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Article
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1997
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Elsevier Science
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English
β 440 KB
Mechamsms for the ring conventon of GTP mto cofactor precursors by GTP cyclohydrolases and molybdopterin synthase are proposed and discussed III the context of the crystal structllre of the GTP cyclohydrolase I -2'-deoxy-GTT' complex The mechatusms suggest that common features of acid-base catalysis