On the mechanism of human intestinal absorption
β Scribed by Michael H. Abraham; Yuan H. Zhao; Joelle Le; Anne Hersey; Christopher N. Luscombe; Derek P. Reynolds; Gordon Beck; Brad Sherborne; Ian Cooper
- Book ID
- 108422044
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 198 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0223-5234
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## Abstract Calcium is absorbed in the mammalian small intestine by two general mechanisms: a transcellular active transport process, located largely in the duodenum and upper jejunum; and a paracellular, passive process that functions throughout the length of the intestine. The transcellular proce
This work describes the modeling of human intestinal absorption using one-and two-descriptor nonlinear models. Molecules with known transport mechanisms other than passive transport were removed from the dataset. The human intestinal absorption data were fitted to symmetric and asymmetric sigmoidal