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On the mechanism of hormone action

✍ Scribed by Beato, Miguel; Brände, Wilhelm; Biesewig, Dirk; Sekeris, Constantin E.


Book ID
121948493
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
709 KB
Volume
208
Category
Article
ISSN
0304-4165

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✍ Gordon H. Sasaki; Dr. Benjamin S. Leung 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 552 KB

The presence of ER in DMBA-tumors was demonstrated by the use of dextrancharcoal assay, sephadex chromatography, sucrose gradient sedimentation, and organ culture techniques. It was found that tumors have binding sites ranging from 10-" to 10-l' moles/mg protein, and a dissociation constant of ER 10