In the perfused rat liver administration of glucagon was shown to result in a transiently increased uptake of K+, indicating the possible involvement of the Na+, K+-ATPase. Direct measurement of the activity of Na+, K+-ATPase revealed a two-fold stimulation of the enzyme by glucagon. The effect of g
On the mechanism of glucagon stimulation of hepatic gluconeogenesis
✍ Scribed by Matilde S. Ayuso-Parrilla; Angeles Martín-Requero; Roberto Parrilla
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 449 KB
- Volume
- 370
- Category
- Article
- ISSN
- 0031-6768
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Primary cultures of parenchymal cells isolated from adult rat liver by a collagenase perfusion procedure and maintained as a monolayer in a serum‐free culture medium were used to study glucoeogenesis and the role that the glucocorticoids play in the control of this pathway. These cells
## Abstract The coordinate regulation of gluconeogenesis by the glucocorticoids and glucagon in primary cultures of adult rat liver parenchymal cells has been studied. The results suggest that glucagon stimulation of glucose production from 3‐carbon precursors is composed of at least two components