On the kinetics of oligomer binding
β Scribed by Douglas Poland
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1990
- Tongue
- English
- Weight
- 899 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0006-3525
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β¦ Synopsis
Abstract
The kinetics of oligomer binding to a polymer are treated in the approximation that the internal states of the oligomerβpolymer complex equilibrate rapidly compared with the rate of binding. In that case one can use equilibrium statistical mechanics to give the density of appropriate binding sites required in the kinetic equation. In this manner one can obtain a general differential equation in one variable (the net density of oligomer bound) for the case of cooperative binding. Several simple, but accurate, approximate solutions to the binding kinetics are presented.
π SIMILAR VOLUMES
Human fibrinogen was treated with thrombin in the presence of fibrinoligase (Factor XIIIa) and calcium ion at pH 8.5, ionic strength 0.45, and the ensuing polymerization was interrupted at various time intervals ( t ) both before and after the clotting time (t,) by solubilization with a solution of
## Abstract Human fibrinogen was treated with thrombin in the presence of fibrinoligase (Factor XIIIa) and calcium ion at pH 8.5, ionic strength 0.45, and the ensuing polymerization was interrupted at various time intervals (__t__) both before and after the clotting time (__t__~__c__~) by solubiliz
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