## Abstract The interpretation of the results of large association studies encompassing much or all of the human genome faces the fundamental statistical problem that a correspondingly large number of single nucleotide polymorphisms markers will be spuriously flagged as significant. A common method
✦ LIBER ✦
On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies
✍ Scribed by Ann-Kristin Petersen, Jan Krumsiek, Brigitte Wägele, Fabian J Theis, H-Erich Wichmann, Christian Gieger, Karsten Suhre
- Book ID
- 119894146
- Publisher
- BioMed Central
- Year
- 2012
- Tongue
- English
- Weight
- 210 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1471-2105
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
On multiple-testing correction in genome
✍
Valentina Moskvina; Karl Michael Schmidt
📂
Article
📅
2008
🏛
John Wiley and Sons
🌐
English
⚖ 144 KB
👁 1 views
Testing for genetic association in the p
✍
Kai Wang
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 449 KB
👁 2 views
## Abstract Genome‐wide case‐control association study is gaining popularity, thanks to the rapid development of modern genotyping technology. In such studies, population stratification is a potential concern especially when the number of study subjects is large as it can lead to seriously inflated
A Genome-wide Association Study of the H
✍
Rhee, Eugene P.; Ho, Jennifer E.; Chen, Ming-Huei; Shen, Dongxiao; Cheng, Susan;
📂
Article
📅
2013
🏛
Elsevier Science
🌐
English
⚖ 917 KB
lrgpr: interactive linear mixed model an
✍
Hoffman, G. E.; Mezey, J. G.; Schadt, E. E.
📂
Article
📅
2014
🏛
Oxford University Press
🌐
English
⚖ 65 KB
Efficient Two-Step Testing of Gene-Gene
✍
Lewinger, Juan Pablo; Morrison, John L.; Thomas, Duncan C.; Murcray, Cassandra E
📂
Article
📅
2013
🏛
John Wiley and Sons
🌐
English
⚖ 450 KB
[Methods in Molecular Biology] Genome-Wi
✍
Gondro, Cedric; van der Werf, Julius; Hayes, Ben
📂
Article
📅
2013
🏛
Humana Press
⚖ 208 KB