On the helix-coil equilibrium in two- and three-stranded complexes involving complementary poly- and oligonucleotides

The thermodynamic contribution of the 5-

The thermodynamic contribution of the 5-methyl group of thymine in the two- and three-stranded complexes formed by poly(dU) and poly(dT) with poly(dA)

✍ Philip D. Ross; Frank B. Howard 📂 Article 📅 2003 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 168 KB 👁 2 views

## Abstract To assess the thermodynamic contribution of the 5‐methyl group of thymine, we have studied the two‐stranded helical complexes poly(dA) · poly(dU) and poly(dA) · poly(dT) and the three‐stranded complexes—poly(dA) · 2poly(dU), poly(dA) · poly(dT) · poly(dU) and poly(dA) · 2poly(dT)—by dif