✦ LIBER ✦

On the growth and stability of cell cultures and solid tumors

✍ Scribed by H.P. Greenspan

Publisher: Elsevier Science
Year: 1976
Tongue: English
Weight: 682 KB
Volume: 56
Category: Article
ISSN: 0022-5193
DOI: 10.1016/s0022-5193(76)80054-9

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✦ Synopsis

A theory is formulated to describe the growth and movement of certain cell cultures and solid tumors in response to an arbitrary distribution of nutrient. Conditions are established for the unstable development of a colony in which internal pressure forces overcome surface tension and adhesion. Instability is manifested as either a pinch or a corrugation of the boundary surface which can cause a spheroidal distortion of colony shape and may possibly lead to subdivision or disintegration. It is further shown that colonies which share the same food supply repel each other and move apart.

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