On the global solution to nonlinear model predictive control algorithms that use polynomial models

Use of in vitro human skin membranes to

Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes

✍ Sheree E. Cross; Michael S. Roberts 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 1 views

The effect of dermal clearance on epidermal concentrations of topically applied drugs is poorly understood but fundamental to absorption kinetics and efficacy. Previously generated data quantifying changes in flux and epidermal retention of a series of alcohols and steroids was used to relate solute