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On the function of nitrogenase FeMo cofactors and competitive catalysts: chemical principles, structural blue-prints, and the relevance of iron sulfur complexes for N2 fixation

✍ Scribed by Dieter Sellmann; Jürgen Utz; Nicole Blum; Frank W. Heinemann


Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
469 KB
Volume
190-192
Category
Article
ISSN
0010-8545

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✦ Synopsis


This article tries to rationalize why low molecular weight complexes have not yet been able to copy nitrogenase catalyzed reactions or to act as competitive catalysts with nitrogenaselike activity. An answer is sought in that such complexes must rather fulfil the principles governing FeMoco function than duplicate its structure. Such principles, e.g. metal sulfur bonds, reversible M-S bond dissociation, Brønsted basicity, vacant sites, redox activity, are illustrated with metal complexes of multidentate thioether thiolate ligands.