On the Enantioselectivity of a 2-Aza-divinylcyclopropane Rearrangement
✍ Scribed by Paul Müller; Hassan Imogai
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- German
- Weight
- 112 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0018-019X
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## Abstract The highly enantioselective organocatalytic domino aza‐Michael/aldol reaction is presented. The unprecedented, chiral amine‐catalyzed asymmetric domino reactions between 2‐aminobenzaldehydes and α,β‐unsaturated aldehydes proceed with excellent chemo‐ and enantioselectivity to give the c
The external chiral ligand-induced enantioselective [2,3]-Wittig rearrangements of crotyl benzyl ethers and crotyl propargylic ethers are described. The most notable is that treatment of (E)-crotyl propargylic ethers with a t-butyllithium/(S;S)-bis(oxazoline) complex provides a relatively high enant