The contribution of HIV fitness to the e
โ
Elijah Paintsil; Asa Margolis; Jennifer A. Collins; Louis Alexander
๐
Article
๐
2006
๐
John Wiley and Sons
๐
English
โ 104 KB
All currently recommended anti-retroviral therapy protocols employ reverse transcriptase inhibitors (RTIs). However, mutations within the reverse transcriptase (RT) domain can lead to resistance to these agents and treatment failure. The contribution of the fitness of drug-resistant species to the e