Lithium diorganocuprates are now widely used in conjugate additions to a,a-unsaturated car-bony1 compounds' and in coupling reactions with alkyl halides2, allyli~acetates~, and other compounds possessing good leaving groups. Here we report a new reaction of lithium dialkylcuprates which is formally
On the conformational flexibility of model compounds of β-substituted α, β-unsaturated peptides
✍ Scribed by David Ajò; Maurizio Casarin; Gaetano Granozzi
- Book ID
- 119115808
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 261 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0166-1280
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## Abstract The full conformational space was explored for an achiral and two chiral β‐peptide models: namely For‐β‐Ala‐NH~2~, For‐β‐Abu‐NH~2~, and For‐β‐Aib‐NH~2~. Stability and conformational properties of all three model systems were computed at different levels of theory: RHF/3‐21G, B3LYP/6‐311
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