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On the Claisen Rearrangement of Allyl Ethyl Ketene Acetals Generated in situ via Benzeneselenenic Acid Eliminiation

✍ Scribed by Rita Pitteloud; Martin Petrzilka


Book ID
102251930
Publisher
John Wiley and Sons
Year
1979
Tongue
German
Weight
438 KB
Volume
62
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Mixed acetals 7 of benzeneseleninylacetaldehyde, prepared by a simple 2‐step procedure from mono‐ and bicyclic allylic alcohols 5, undergo benzeneselenenic acid elimination to transient ketene acetals 8 which afford γ, δ‐unsaturated esters 9 via the ester Claisen rearrangement (Scheme 2). Under the same conditions selenoxide 7h derived from benzyl alcohol 5h is converted back to benzyl alcohol with the concomitant formation of ethylphenylselenoacetate 12.