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On the activation mechanism of store-operated calcium channels

✍ Scribed by Anant B. Parekh

Publisher
Springer
Year
2006
Tongue
English
Weight
230 KB
Volume
453
Category
Article
ISSN
0031-6768

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πŸ“œ SIMILAR VOLUMES

Inhibitors of store-operated calcium cha
Inhibitors of store-operated calcium channels: Imidazoles, phenothiazines, and other tricyclics
✍ Jacquie L. Harper; John W. Daly πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 284 KB

Imidazoles, such as SKF 96365, clotrimazole, and miconazole, have represented the major class of inhibitors of store-operated calcium (SOC) channels. In HL60 cells, ATP and thapsigargin cause depletion of intracellular calcium stores, resulting in activation of SOC channels. Tricyclic phenothiazines