On the absolute stereochemistry of C-2 and C-3 in stegobinone
โ Scribed by Reinhard W. Hoffmann; Wolfgang Ladner
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 209 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
By comparison of the CD-spectra of synthetic material with that of stegobinone it is established that stegobinone has the 2S,3R-configuration. The stereochemistry at C-7 remains unknown at present.
๐ SIMILAR VOLUMES
C-3 took place to some extent. The crude 2 was oxidized under the Swern condition to give (2S,3IZ,l'R)-stegobinone 1 in 14.0 % yield from 3 after purification by prep TLC. The unwanted by-product, (2S,3S,l'R)-stegobinone, could be removed by TLC separation. The IR and mass spectral properties of our
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