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On some derivatives of ferrocene, novel acetylcholinesterase inhibitors

✍ Scribed by Dr. Bogumil Hetnarski; Abel Lajtha; Henryk M. Wisniewski

Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
236 KB
Volume
5
Category
Article
ISSN
0360-4012

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✦ Synopsis

Abstract

Eight novel methylcarbamates, derivatives of ferrocenylketoximes and aldoximes, and ferrocenyl‐p‐hydroxyphenylaldimine were prepared. They are the first carbamates in the field of ferrocene derivaties. Their anticholinesterase activity was tested and found to fall in the range of 10^−4^ through 10^−6^ M (I~50~). The correlation between the activity of the compounds and the kind of substitutents grafted on the methylene carbon atom is discussed.

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