On poor and not so poor thought experiments. A reply to Daniel Cohnitz

Ineffective expression of CD40 ligand on

Ineffective expression of CD40 ligand on cord blood T cells may contribute to poor immunoglobulin production in the newborn

✍ Duilio Brugnoni; Paolo Airò; Daniel Gralfu; Massimo Marconiu; Morena Lebowitzu; 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 618 KB

## Abstract A major feature of the immature immune system in the newborn is its inability to produce significant levels of immunoglobulins other than IgM in response to antigens. It has recently been demonstrated that interaction of the CD40 molecule on B cells with the CD40 ligand (CD40L) on activ