𝔖 Bobbio Scriptorium
✦   LIBER   ✦

On Combining Family-Based and Population-Based Case–Control Data in Association Studies

✍ Scribed by Yingye Zheng; Patrick J. Heagerty; Li Hsu; Polly A. Newcomb


Book ID
109224333
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
198 KB
Volume
66
Category
Article
ISSN
0006-341X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


On combining family and case-control stu
✍ Ruth M. Pfeiffer; David Pee; Maria T. Landi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 144 KB

## Abstract Studies to detect genetic association with disease can be family‐based, often using families with multiple affected members, or population based, as in population‐based case‐control studies. If data on both study types are available from the same population, it is useful to combine them

Sample size calculations for population-
✍ Ruth M. Pfeiffer; Mitchell H. Gail 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 205 KB

## Abstract Most previous sample size calculations for case‐control studies to detect genetic associations with disease assumed that the disease gene locus is known, whereas, in fact, markers are used. We calculated sample sizes for unmatched case‐control and sibling case‐control studies to detect

Genome-wide association studies: quality
✍ Andreas Ziegler 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 139 KB

## Abstract Genome‐wide association studies, using hundreds of thousands of single‐nucleotide polymorphism (SNP) markers, have become a standard approach for identifying disease susceptibility genes. The change in the technology poses substantial computational and statistical challenges that have b