On-Chip Alginate Microencapsulation of Functional Cells
✍ Scribed by Victoria L. Workman; Stephen B. Dunnett; Peter Kille; Daniel D. Palmer
- Book ID
- 102497323
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 277 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1022-1336
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
We report the use of a PTFE‐based microfluidic device for the encapsulation of living, therapeutically‐active cells within monodisperse alginate microspheres. We present a novel microfluidic platform and a flexible experimental method for the production of alginate microspheres. Cell lines HEK293, U‐2 OS and PC12 were separately encapsulated using this method, with minimal loss of cell viability.
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