Allele frequencies are generally estimated with data on a set of unrelated individuals. In genetic studies of late-onset diseases, the founding individuals in pedigrees are often not available, and so one is confronted with the problem of estimating allele frequencies with data on related individual
โฆ LIBER โฆ
On allele frequency computation from DNA typing data
โ Scribed by Ranajit Chakraborty; Li An; Yixi Zhong; M. R. Srinivasan; Bruce Budowle
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- German
- Weight
- 316 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0937-9827
No coin nor oath required. For personal study only.
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In the April 2001 issue of Genetic Epidemiology, in the article ''Estimation of Allele Frequencies With Data on Sibships,'' by , there is an error on page 310, in the second paragraph under ''Method 3: Accounting for Relationships.'' The stated probabilities that an allele in the second sibling is n