The synthesis of the trisaccharide c ! -L-Fuc~-( 1 +2)-p-o-Ga1pp-( 1 +3)-P-~-GalpNAc-l-OPr (2) is described. The N-acetylgalactosamine 6 was obtained from 4 by an intramolecular displacement of a (trifluo-romethy1)sulfonyloxy by a pivaloyloxy group with its concomitant migration from position 3 to p
Oligosaccharides related to tumor-associate antigens. Part 3. Synthesis of the propyl glycosides of the trisaccharide β-D-Galp-(1→3)-β-D-GalpNAc-(1→3)-α-D-Galp and of the Tetrasaccharide α-L-Fucp-(1→2)-β-D-Galp-(1→3)-β-D-GalpNAc-(1→3)-α-D-Galp, components of a tumor antigen recognized by the antibody MBr1
✍ Scribed by Luigi Lay; Luigi Panza; Giovanni Russo; Diego Colombo; Fiamma Ronchetti; Elena Adobati; Silvana Canevari
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- German
- Weight
- 411 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Synthesis of the
Propyl Glycosides of the TrisaccharideP-D-Galp-(l+3)-P-D-GalpNAc-(1+3)-a-D-Galp and of the Tetrasaccharide E-L-Fuc~-(~+~)-/?-D-Galp-(1+3)-j?-~-GalpNAc-(1+3)-a-D-Galp, Components of a Tumor Antigen ') part 2: [I].
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