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Oligonucleotide (ODN) fluorescence in situ hybridization (Oligo-FISH) and conventional FISH allow enumeration of 24 chromosomes in 6 successive hybridizations performed in a single day

โœ Scribed by J. Aurich-Costa; C. Ng; S. Selvaggio; P. Colls; S. Bradley


Book ID
116476160
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
40 KB
Volume
92
Category
Article
ISSN
1556-5653

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## Abstract Patients with acute myeloid leukemia (AML) and a complex aberrant karyotype have a poor outcome despite intensive antileukemic treatment. The aim of this study was to analyze in detail the genetic abnormalities in this subgroup of AML. Therefore, 125 AML cases with complex aberrant kary