Oligonucleotide aptamers that recognize small molecules
β Scribed by Michael Famulok
- Book ID
- 114314880
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 725 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0959-440X
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## Abstract Molecular recognition of small molecule ligands by the nucleic acid aptamers for tobramycin, ATP, and FMN has been examined using electrospray ionization mass spectrometry (ESIβMS). Mass spectrometric data for binding stoichiometry and relative binding affinity correlated well with solu
Aminoglycosides are a structurally diverse family of aminosugar and aminocyclitol derivatives that are currently the only well-characterized class of small molecules that selectively bind RNA, [1] including sites on prokaryotic 16S rRNA which is believed to be the locus of aminogylcoside antibiotic