Oligomerization Route to Py−Im Polyamide Macrocycles
✍ Scribed by Chenoweth, David M.; Harki, Daniel A.; Dervan, Peter B.
- Book ID
- 126022625
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 664 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
We wish to report convenient syntheses of the macrocyclic amides, l\_andH, and their amine NO. 6 9 derivatives. An attempt to establish ;;e presence in L of a strong transannularhydrogen bond,by nmr exchange studies in D20-DMSO have thus far failed, due to the difficulty of obtaining data of precisi
The 1:1 and 2:2 cyclization reactions were simultaneously observed by addition ofdiethyl oxalate on 3,3,10,10-tetramethyl-1,5,8, l 2-tetraazadodecane. The resulting 1 : 1 cyclisation product was fully characterized by spectroscopy and X-ray diffraction study. The reduction of this compound gives the