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Oligomeric amyloid-β peptide affects the expression of genes involved in steroid and lipid metabolism in primary neurons

✍ Scribed by Bilal Malik; Cathy Fernandes; Richard Killick; Richard Wroe; Alessia Usardi; Ritchie Williamson; Stuart Kellie; Brian H. Anderton; C. Hugh Reynolds


Book ID
116765868
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
779 KB
Volume
61
Category
Article
ISSN
0197-0186

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## Abstract Recently, we have found that alterations in cellular cholesterol metabolism are involved in promotion of tau phosphorylation (Fan et al. [2001] J. Neurochem. 76: 391–400; Sawamura et al. [2001] J. Biol. Chem. 276:10314–10319). In addition, we have shown that amyloid β‐protein (Aβ) promo