Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system leading to selective destruction of myelin sheaths and/or oligodendrocytes. The immunological mechanisms responsible for myelin destruction and the primary target of the immune response have not yet been identifi
✦ LIBER ✦
Oligodendrocytes in the early course of multiple sclerosis
✍ Scribed by Wolfgang Brück; Mascha Schmied; Gerda Suchanek; Yvonne Brück; Helene Breitschopf; Sigrid Poser; Sara Piddlesden; Dr. Hans Lassmann
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 958 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0364-5134
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## Abstract Oligodendrocyte‐specific protein (OSP) is concentrated in CNS myelin and is a potential autoantigen in the development of multiple sclerosis (MS). We performed proliferation assays with lymphocytes from MS patients and normal controls. OSP peptide‐induced proliferation was common in rel
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