✦ LIBER ✦

Olfactory function in restless legs syndrome

✍ Scribed by Dr. Charles H. Adler; Katrina A. Gwinn; Stephanie Newman

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 276 KB
Volume: 13
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870130332

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Restless leg syndrome (RLS) is usually idiopathic but may occur in patients with Parkinson's disease (PD). Both respond to dopaminergic medications. Whether these disorders share a common pathophysiology is unclear. Because PD is associated with a loss of olfactory function, we compared the olfactory function, we compared the olfactory function of patients with RLS with control and PD patients. Using the University of Pennsylvania Smell Identification Test (UPSIT), olfactory function was found to be normal in patients with idiopathic RLS and significantly reduced in patients with PD. This suggests that the pathophysiology of RLS differs from PD, and that RLS likely is not a “forme fruste” or a preclinical sign of PD.

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