The lupane-type triterpene betulinic acid was isolated from an ethanol extract of the root bark of the Tanzanian tree Uapaca nitida Mu ยจll-Arg. (Euphorbiaceae). The in vitro antiplasmodial IC 50 values of betulinic acid against chloroquine resistant (K1) and sensitive (T9-96) Plasmodium falciparum w
Oleuropein evaluated in vitro and in vivo as an antioxidant
โ Scribed by E. Speroni; M. C. Guerra; A. Minghetti; N. Crespi-Perellino; P. Pasini; F. Piazza; A. Roda
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 75 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-418X
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โฆ Synopsis
Oleuropein is a phenolic compound extracted from the leaves of Olea europaea. The antioxidant activity of this natural product has been evaluated in vitro and in vivo by means of a chemiluminescent assay, based on a luminol-horseradish peroxidase p-iodophenol O 2 mediated light emission system. In vitro, oleuropein had a remarkable antioxidant activity. Serum samples obtained from treated animals exhibited an antioxidant activity comparable to controls. Bile samples obtained from the same treated animals showed a significant inhibition (90%) of the light emission in the chemiluminescent assay, when compared with the control sample.
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