Human Aβ1–42 reduces iron-induced toxici
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Glenda M. Bishop; Stephen R. Robinson
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Article
📅
2003
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John Wiley and Sons
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English
⚖ 351 KB
## Abstract Senile plaques, the major neuropathological lesions of Alzheimer's disease (AD), are composed primarily of amyloid‐β (Aβ) peptide and contain high concentrations of iron (1.0 mM). We have previously shown that intracortical injections of 1.0 mM iron to adult rats produce significantly m