Olefin Metathesis Route to Antiviral Nucleosides
✍ Scribed by Luigi A. Agrofoglio; Steven P. Nolan
- Book ID
- 101990897
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 8 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
Various 1-methylene glucose derivatives afforded after ring closure olefin metathesis cyclic polyethers and C-glycoside precursors.
## Abstract Ru‐Catalyzed olefin cross‐metathesis (CM) has been successfully applied to the synthesis of several phytyl derivatives (2b, 2d–f, 3b) with a trisubstituted CC bond, as useful intermediates for an alternative route to __α__‐tocopheryl acetate (vitamin E acetate; 1b) (__Scheme 1__). Usin
## Abstract A novel procedure is elaborated for the preparation of a ruthenium complex, which is successfully applied as a catalyst in ring‐closing metathesis and cross‐metathesis reactions.