Of Timing and Surrogates: A Way Forward for Cancer Chemoprevention
β Scribed by Thompson, P. A.; Gerner, E. W.
- Book ID
- 125447398
- Publisher
- American Association for Cancer Research
- Year
- 2011
- Tongue
- English
- Weight
- 219 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1078-0432
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Surrogate endβpoint biomarkers are being developed as indicators of the efficacy of chemopreventive agents. These biomarkers are molecular and biological endβpoints that can be modulated by chemopreventive agents in accordance with their efficacy to prevent cancer. DNA hypomethylation i
Progression of breast neoplasia is characterized by a variety of causal and nonspecific molecular, karyotypic, and cellular level genetic alterations. These include allelic losses, chromosomal rearrangements, and aneusomies, as well as widely divergent clonal DNA content aberrations. Establishment o