Ocular Fluid Dynamics: Anatomy, Physiology, Imaging Techniques, and Mathematical Modeling

✍ Scribed by Giovanna Guidoboni, Alon Harris, Riccardo Sacco

• Publisher: Springer International Publishing;Birkhäuser
• Year: 2019
• Tongue: English
• Leaves: 606
• Series: Modeling and Simulation in Science, Engineering and Technology
• Edition: 1st ed. 2019
• Category: Library

✦ Synopsis

The chapters in this contributed volume showcase current theoretical approaches in the modeling of ocular fluid dynamics in health and disease. By including chapters written by experts from a variety of fields, this volume will help foster a genuinely collaborative spirit between clinical and research scientists. It vividly illustrates the advantages of clinical and experimental methods, data-driven modeling, and physically-based modeling, while also detailing the limitations of each approach. Blood, aqueous humor, vitreous humor, tear film, and cerebrospinal fluid each have a section dedicated to their anatomy and physiology, pathological conditions, imaging techniques, and mathematical modeling. Because each fluid receives a thorough analysis from experts in their respective fields, this volume stands out among the existing ophthalmology literature.
Ocular Fluid Dynamics is ideal for current and future graduate students in applied mathematics and ophthalmology who wish to explore the field by investigating open questions, experimental technologies, and mathematical models. It will also be a valuable resource for researchers in mathematics, engineering, physics, computer science, chemistry, ophthalmology, and more.

✦ Table of Contents

Front Matter ....Pages i-xiv
Front Matter ....Pages 1-1
Mathematical and Physical Modeling Principles of Complex Biological Systems (Riccardo Sacco, Giovanna Guidoboni, Aurelio Giancarlo Mauri)....Pages 3-20
Front Matter ....Pages 21-21
Vascular Anatomy and Physiology of the Eye (Daniele Prada, Alon Harris, Giovanna Guidoboni, Lucas Rowe, Alice Chandra Verticchio-Vercellin, Sunu Mathew)....Pages 23-45
Pathological Consequences of Vascular Alterations in the Eye (Daniele Prada, L. Rowe, A. Hajrasouliha, T. Ciulla, I. Januleviciene, G. Chiaravalli et al.)....Pages 47-70
Measurement of Geometrical and Functional Parameters Related to Ocular Blood Flow (Josh Gross, Daniele Prada)....Pages 71-99
Mathematical Modeling of Blood Flow in the Eye (Julia Arciero, Lucia Carichino, Simone Cassani, Giovanna Guidoboni)....Pages 101-157
Front Matter ....Pages 159-159
Changes in Parameters of Aqueous Humor Dynamics Throughout Life (Carol B. Toris, George Tye, Padmanabhan Pattabiraman)....Pages 161-190
Aqueous Humor Dynamics and Its Influence on Glaucoma (Frances Meier-Gibbons, Marc Töteberg-Harms)....Pages 191-213
Approaches to Aqueous Humor Outflow Imaging (Jenna Tauber, Larry Kagemann)....Pages 215-225
Mathematical Models of Aqueous Production, Flow and Drainage (Mariia Dvoriashyna, Jan O. Pralits, Jennifer H. Tweedy, Rodolfo Repetto)....Pages 227-263
Front Matter ....Pages 265-265
Vitreous Physiology (Gian Paolo Giuliari, Peter Bracha, A. Bailey Sperry, Thomas Ciulla)....Pages 267-275
Vitreous Pathology (Peter Bracha, Gian Paolo Giuliari, Thomas A. Ciulla)....Pages 277-287
Vitreous Imaging (Adam T. Chin, Caroline R. Baumal)....Pages 289-302
Mathematical Models of Vitreous Humour Dynamics and Retinal Detachment (Rodolfo Repetto, Mariia Dvoriashyna)....Pages 303-325
Front Matter ....Pages 327-327
The Tear Film: Anatomy and Physiology (Vikram Paranjpe, Lam Phung, Anat Galor)....Pages 329-345
The Tear Film: Pathological Conditions (Vikram Paranjpe, Anat Galor)....Pages 347-371
Imaging Techniques for the Visualization and Evaluation of Tear Film Dynamics (Jinxin Huang, Jannick P. Rolland)....Pages 373-385
Mathematical Models of the Tear Film (Richard J. Braun, Tobin A. Driscoll, Carolyn G. Begley)....Pages 387-432
Front Matter ....Pages 433-433
Anatomy and Physiology of the Cerebrospinal Fluid (David Fleischman, John Berdahl)....Pages 435-450
Pathological Consequences of Reduced Cerebrospinal Fluid Pressure: Experimental Studies (Zheng Zhang, Jing Li, Xiaoxia Li, Ningli Wang)....Pages 451-468
Instruments to Measure and Visualize Geometrical and Functional Parameters Related to the Fluid Dynamics of Cerebrospinal Fluid in the Eye (Ingrida Januleviciene, Lina Siaudvytyte)....Pages 469-496
Mathematical Modeling of the Cerebrospinal Fluid Flow and Its Interactions (Lorenzo Sala, Fabrizia Salerni, Marcela Szopos)....Pages 497-540
Front Matter ....Pages 541-541
Image Analysis for Ophthalmology: Segmentation and Quantification of Retinal Vascular Systems (Kannappan Palaniappan, Filiz Bunyak, Shyam S. Chaurasia)....Pages 543-580
The Next Frontier of Imaging in Ophthalmology: Machine Learning and Tissue Biomechanics (Jenna Tauber, Larry Kagemann)....Pages 581-597
Statistical Methods in Medicine: Application to the Study of Glaucoma Progression (Alessandra Guglielmi, Giovanna Guidoboni, Alon Harris, Ilaria Sartori, Luca Torriani)....Pages 599-612

✦ Subjects

Mathematics; Mathematical Modeling and Industrial Mathematics; Physiological, Cellular and Medical Topics; Computational Science and Engineering; Soft and Granular Matter, Complex Fluids and Microfluidics