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Ocular findings in patients with solid tumours treated with the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (‘Iressa’, ZD1839) in Phase I and II clinical trials

✍ Scribed by Murray, P I; Bristow, E; Forsythe, B J; Faulkner, K; Tullo, A B; Esmaeli, B


Book ID
110035717
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
187 KB
Volume
19
Category
Article
ISSN
0950-222X

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Follicular and epidermal alterations in
✍ R. Van Doorn; G. Kirtschig; E. Scheffer; T.J. Stoof; G. Giaccone 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 131 KB

We report the cutaneous side-effects of ZD1839 (Iressa), a new anticancer agent that acts by inhibiting epidermal growth factor (EGF) receptor signal transduction. Three patients receiving ZD1839 developed an eruption consisting of follicular papules and pustules in an acneiform distribution as well